Flexible Workflow

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R package & Standalone tool.

Spatial expression data compatibility

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Image-based (CosMX, Zenium).
Array-based (Visium, Stereo-seq).

Key advantages

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Resolves spatial heterogeneity.
Biological interpretation of spatial patterns.
Robust to noise and cross-platform.

Integrated analysis

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Cell composition profiling.
Functional distances and intersections.

Functional Islands

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Spatial gene set enrichment to identify tissue functional modules.